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- 1DJ Khaled, Maura Tierney, Joaquin Consuelos, guest co-host Christian SlaterSeptember 5, 2016
- 2Chris Noth, Bradley Whitford, Martina McBride, guest co-host Morris ChestnutSeptember 6, 2016
- 3Aaron Eckhart, Ben McKenzie, guest co-host Morris ChestnutSeptember 7, 2016
- 4Meg Ryan, George Eads, guest co-host Anderson CooperSeptember 8, 2016
- 5Jessica Alba, Terrence Howard, guest co-host Anderson CooperSeptember 9, 2016
- 6Patrick Dempsey, Sophia Loren, guest co-host Chris HarrisonSeptember 12, 2016
- 7Joseph Gordon-Levitt, Carol Burnett, the newly-crowned Miss America, guest co-host Michael WeatherlySeptember 13, 2016
- 8Renee Zellweger, Jaimie Alexander, Vern Yip, guest co-host Neil Patrick HarrisSeptember 14, 2016
- 9Colin Firth, Bill O'Reilly, Jacob Whitesides, guest co-host Neil Patrick HarrisSeptember 15, 2016
- 10Billie Lourd, AJR, guest co-host Neil Patrick HarrisSeptember 16, 2016
- 11Kevin James, Rachael Harris, Mike Posner, guest co-host Busy PhilippsSeptember 19, 2016
- 12Scott Bakula, guest co-host Jussie SmollettSeptember 20, 2016
- 13Kiefer Sutherland, Ken Jeong, guest co-host Jussie SmollettSeptember 21, 2016
- 14Juliette Lewis, Brad Keselowski, guest co-host Mark ConsuelosSeptember 22, 2016
- 15Denzel Washington, Brian "Q" Quinn, James "Murr" Murray, Sal Vulcano, Joe Gatto, guest co-host Chris PrattSeptember 23, 2016
- 16Rob Lowe, Will Forte, Elle King, guest co-host Josh GrobanSeptember 26, 2016
- 17Samuel L. Jackson, Mandy Moore, Kristin Chenoweth, guest co-host Josh GrobanSeptember 27, 2016
- 18Tom Selleck, January Jones, Ingrid Michaelson, guest co-host Jerry O'ConnellSeptember 28, 2016
- 19Morgan Freeman, Kevin McKidd, guest co-host Jerry O'ConnellSeptember 29, 2016
- 20Mark Wahlberg, Priyanka Chopra, guest co-host Jerry O'ConnellSeptember 30, 2016
- 21Kenan Thompson, Chris Gethard, guest co-host Jerry O'ConnellOctober 3, 2016
- 22Justin Theroux, Lindsey Vonn, Melissa Etheridge, guest co-host Fred SavageOctober 4, 2016
- 23Ted Danson, Anne Heche, Tom Odell, guest co-host Fred SavageOctober 5, 2016
- 24Ben Affleck, Danai Gurira, guest co-host Fred SavageOctober 6, 2016
- 25Sarah Paulson, Laura Prepon, Colbie Caillat, guest co-host Ashton KutcherOctober 7, 2016
- 26Jeffrey Dean Morgan, Jennifer Morrison, Brian "Q" Quinn, James "Murr" Murray, Sal Vulcano, Joe Gatto, guest co-host Zachary QuintoOctober 10, 2016
- 27Bryan Cranston, Carson Kressley, Aly Raisman, guest co-host Tyler PerryOctober 11, 2016
- 28Jon Hamm, Minnie Driver, Daya, guest co-host Anderson CooperOctober 12, 2016
- 29Tea Leoni, Norman Reedus, Andy Grammer, guest co-host Carrie Ann InabaOctober 13, 2016
- 30J.K. Simmons, Gavin DeGraw, guest co-host Carrie Ann InabaOctober 14, 2016
- 31Vin Diesel, Carole Bayer Sager, guest co-host Sam ChampionOctober 17, 2016
- 32David Hyde Pierce, Victoria Justice, guest co-host Matt BomerOctober 18, 2016
- 33Ewan McGregor, Jeff Gordon, guest co-host CiaraOctober 19, 2016
- 34Matt LeBlanc, Dakota Fanning, guest co-host John LeguizamoOctober 20, 2016
- 35Elijah Wood, Sullivan Stapleton, guest co-host Richard CurtisOctober 21, 2016
- 36Tom Hanks, guest co-host Michael BubleOctober 24, 2016
- 37John Lithgow, Phil Collins, Tyler Glenn, guest co-host Michael BubleOctober 25, 2016
- 38Blair Underwood, Abbi Jacobson, guest co-host Michael BubleOctober 26, 2016
- 39Uzo Aduba, Daniel Sunjata, guest co-host Joel McHaleOctober 27, 2016
- 40Jeremy Irons, guest co-host Joel McHaleOctober 28, 2016
- 41Kevin James, guest co-host Jerry O'ConnellOctober 31, 2016
- 42Benedict Cumberbatch, Gabrielle Union, guest co-host Scott WolfNovember 1, 2016
- 43Donnie Wahlberg, Lauren Cohan, guest co-host Vince VaughnNovember 2, 2016
- 44Rachel Bloom, Kal Penn, guest co-host Christian SlaterNovember 3, 2016
- 45Kyra Sedgwick, Josh Radnor, guest co-host Christian SlaterNovember 4, 2016
- 46Sarah Jessica Parker, Jared Padalecki, guest co-host Richard CurtisNovember 7, 2016
- 47Miles Teller, Daveed Diggs, guest co-host Tony GoldwynNovember 8, 2016
- 48Naomi Watts, Michael Ealy, Cam, guest co-host Megyn KellyNovember 9, 2016
- 49Amy Adams, guest co-host Alex RodriguezNovember 10, 2016
- 50Jeremy Renner, Claire Foy, guest co-host Chris HardwickNovember 11, 2016
- 51Aaron Eckhart, Ali Wentworth, Ming Tsai, guest co-host Billy GardellNovember 14, 2016
- 52Billy Bob Thornton, Robert Wagner, guest co-host Andy CohenNovember 15, 2016
- 53Trevor Noah, One Republic, guest co-host Ryan SeacrestNovember 16, 2016
- 54Dennis Quaid, Sterling K. Brown, guest co-host Ryan SeacrestNovember 17, 2016
- 55William H. Macy, Dev Patel, guest co-host Ryan SeacrestNovember 18, 2016
- 56Maura Tierney, Katie Brown, guest co-host Max GreenfieldNovember 21, 2016
- 57Kristin Davis, the winner of the 2016 NASCAR Sprint Cup Series, Wendy Bazilian, guest co-host Max GreenfieldNovember 22, 2016
- 58Chris O'Donnell, Bernadette Peters, DNCE, guest co-host Joe JonasNovember 23, 2016
- 59Susan Lucci, Craig Bierko, Pentatonix, guest co-host Andy CohenNovember 25, 2016
- 60Felicity Jones, Travis Fimmel, guest co-host Billy EichnerNovember 28, 2016
- 61Bryshere Gray, Tim Tebow, guest co-host Anderson CooperNovember 29, 2016
- 62Tim Daly, Diego Luna, guest co-host Jeffrey Dean MorganNovember 30, 2016
- 63Matt Czuchry, Chris Byrne, guest co-host Mark ConsuelosDecember 1, 2016
- 64Randall Park, Lance Ulanoff, guest co-host Busy PhilippsDecember 2, 2016
- 65Corbin Bleu, Jason Bateman, Jeffrey DonovanDecember 5, 2016
- 66Kate McKinnon, Riz Ahmed, guest co-host Ilana GlazerDecember 6, 2016
- 67Chris Pratt, Courtney B. Vance, Chrissy Teigen, guest co-host Octavia SpencerDecember 7, 2016
- 68Annette Bening, Rita Ora, Sarah McLachlan, guest co-host Scott WolfDecember 8, 2016
- 69Katie Holmes, Kevin Nealon, Brett Eldredge, guest co-host Taraji P. HensonDecember 9, 2016
- 70Bryan Cranston, Billie Lourd, guest co-host Richard CurtisDecember 12, 2016
- 71Marion Cotillard, Peter Gros, Norah Jones, guest co-host Richard CurtisDecember 13, 2016
- 72Michael Fassbender, Gavin DeGraw, guest co-host Richard CurtisDecember 14, 2016
- 73Arnold Schwarzenegger, Elle Fanning, guest co-host Van JonesDecember 15, 2016
- 74Liam Neeson, guest co-host Mark ConsuelosDecember 16, 2016
- 75Kevin Costner, the cast of "Disney On Ice Presents Follow Your Heart", guest co-host Scott WolfDecember 19, 2016
- 76Sting, guest co-host John MulaneyDecember 20, 2016
- 77Garth Brooks, Trisha Yearwood, the Rockettes, guest co-host Christian SlaterDecember 21, 2016
- 78Kyra Sedgwick, Kal Penn, DJ Khaled, guest co-host Christian SlaterDecember 22, 2016
- 79Tom Hanks, Blair Underwood, Abbi Jacobson, guest co-host Michael BubleDecember 23, 2016
- 80Live's Viewers ChoiceDecember 26, 2016
- 81Jessica Alba, Meg Ryan, Terrence Howard, Geoffrey Zakarian, guest co-host Anderson CooperJanuary 2, 2017
- 82Megan Boone, Dr. Wendy Bazilian, guest co-host Mark CubanJanuary 3, 2017
- 83Benjamin Bratt, Mahershala Ali, Dr. Melina Jampolis, guest co-host Chris HardwickJanuary 4, 2017
- 84Sienna Miller, Hayden Panettiere, guest co-host Chris HardwickJanuary 5, 2017
- 85Kate Beckinsale, Cameron Dallas, guest co-host Chris HardwickJanuary 6, 2017
- 86Josh HollowayJanuary 9, 2017
- 87Kevin Bacon, Queen LatifahJanuary 10, 2017
- 88Andrew GarfieldJanuary 11, 2017
- 89Jude Law, Nia LongJanuary 12, 2017
- 90Neil Patrick Harris, Margo MartindaleJanuary 13, 2017
- 91Brendan Fraser, Lisa Rinna, guest co-host Mark ConsuelosJanuary 16, 2017
- 92Viola Davis, Louie Anderson, guest co-host Christian SlaterJanuary 17, 2017
- 93Idina Menzel, Nina Dobrev, guest co-host Christian SlaterJanuary 18, 2017
- 94Matthew McConaughey, James McAvoy, guest co-host Christian SlaterJanuary 19, 2017
- 95Chris O'Donnell, Bernadette Peters, guest co-host Joe JonasJanuary 20, 2017
- 96Jimmy Smits, Melissa Benoist, Priyanka Chopra, guest co-host Anderson CooperJanuary 23, 2017
- 97John Goodman, Bridget Moynahan, guest co-host Bellamy YoungJanuary 24, 2017
- 98Michael Keaton, Ali Larter, Andrea Arden, guest co-host Scott WolfJanuary 25, 2017
- 99Mike Myers, Milla Jovovich, guest co-host Scott WolfJanuary 26, 2017
- 100Christina Ricci, Lance Ulanoff, Train, guest co-host Scott WolfJanuary 27, 2017
- 101Ricky Gervais, Meaghan Murphy, guest co-host Leslie MannJanuary 30, 2017
- 102Colin Hanks, Kevin Pereira, guest co-host Busy PhilippsJanuary 31, 2017
- 103Carla Gugino, Katie Brown, guest co-host Busy PhilippsFebruary 1, 2017
- 104Keanu Reeves, Jeff Perry, Carson Kressley, guest co-host Carrie Ann InabaFebruary 2, 2017
- 105Guest co-host Carrie Ann InabaFebruary 3, 2017
- 106Tracee Ellis Ross, David Oyelowo, Miss Universe Iris Mittenaere, guest co-host Rita OraFebruary 6, 2017
- 107Archie Panjabi, Nick Viall, guest co-host Mark ConsuelosFebruary 7, 2017
- 108Erika Girardi, Holly Holm, guest co-host Mark ConsuelosFebruary 8, 2017
- 109Will Arnett, Zosia Mamet, guest co-host Jeffrey Dean MorganFebruary 9, 2017
- 110Daymond John, guest co-host Jeffrey Dean MorganFebruary 10, 2017
- 111David Muir, Kal Penn, Jeremy Jordan, James WhiteFebruary 13, 2017
- 112John Leguizamo, Laverne Cox, Adam ScottFebruary 14, 2017
- 113John Leguizamo, Ricky Martin, Christine BaranskiFebruary 15, 2017
- 114Chris Harrison, Chrissy Metz, TimbalandFebruary 16, 2017
- 115Chris Harrison, Malin Akerman, Theresa Caputo, Bebe RexhaFebruary 17, 2017
- 116Anderson CooperFebruary 20, 2017
- 117Zach BraffFebruary 21, 2017
- 118Mark ConsuelosFebruary 22, 2017
- 119Jason DeruloFebruary 23, 2017
- 120Jerry O'ConnellFebruary 24, 2017
- 121Live After Oscar Show 2017 Jerry O'Connell, DJ Khaled, Flo Rida, guest co-host Ryan SeacrestFebruary 27, 2017
- 122Jerry O'Connell, Connie Britton, Ray Liotta, the winner of the Daytona 500February 28, 2017
- 123Jerry O'Connell, Milo Ventimiglia, David BoreanazMarch 1, 2017
- 124Jerry O'Connell, Hugh Jackman, Josh Henderson,March 2, 2017
- 125Jerry O'Connell, Octavia Spencer, Mike PosnerMarch 3, 2017
- 126Glenn Close, Matthew Rhys, Auli'i Cravalho, guest co-host Christian SlaterMarch 6, 2017
- 127Tom Hiddleston, Michelle Dockery, guest co-host Christian SlaterMarch 7, 2017
- 128Keri Russell, guest co-host Christian SlaterMarch 8, 2017
- 129Brie Larson, Peter Krause, guest co-host Christian SlaterMarch 9, 2017
- 130Felicity Huffman, Rupert Friend, guest co-host Christian SlaterMarch 10, 2017
- 131Stanley Tucci, Meaghan Murphy, guest co-host Michael WeatherlyMarch 13, 2017
- 132Elizabeth Banks, Jonny Lee Miller, Nick Viall & Vanessa Grimaldi, Peter Gros, guest co-host Josh GadMarch 14, 2017
- 133Ice Cube, Marc Santa Maria, guest co-host Jason SilvaMarch 15, 2017
- 134Jessica Lange, Jesse Williams, Jen Widerstrom, guest co-host Chris HardwickMarch 16, 2017
- 135Bryan Cranston, Chad Michael Murray, guest co-host Chris HardwickMarch 17, 2017
- 136Jennifer Lopez, John Lithgow, guest co-host Jeffrey Dean MorganMarch 20, 2017
- 137Andrew Garfield, Queen Latifah, Christopher Jackson, guest co-host Jerry O'ConnellMarch 21, 2017
- 138Brendan Fraser, Lisa Rinna, Holly Holm, guest co-host Mark ConsuelosMarch 22, 2017
- 139Jude Law, Matt LeBlanc, guest co-host John LeguizamoMarch 23, 2017
- 140Michael Keaton, Kevin Costner, Andrea Arden, guest co-host Scott WolfMarch 24, 2017
- 141Lisa Kudrow, Andrew McCarthy, "Science Bob" Pflugfelder, guest co-host Mark ConsuelosMarch 27, 2017
- 142Kevin James, Chelsea Handler, Randall Park, Kevin Pereira, guest co-host Busy PhilippsMarch 28, 2017
- 143Viola Davis, James McAvoy, guest co-host Christian SlaterMarch 29, 2017
- 144Matthew McConaughey, Idina Menzel, Rachel Bloom, A Great Big World, guest co-host Christian SlaterMarch 30, 2017
- 145Jonah Hill, Elizabeth Banks, Bryce Dallas Howard, guest co-host Josh GadMarch 31, 2017
- 146Kate Walsh, Henrik Lundqvist, Sarah Michelle Gellar, guest co-host Scott WolfApril 3, 2017
- 147Sally Field, Ellie Kemper, Charo & Keo Motsepe, guest co-host Scott WolfApril 4, 2017
- 148Amanda Peet, Scott Eastwood, guest co-host Scott WolfApril 5, 2017
- 149Pierce Brosnan, Mandy Patinkin, guest co-host Scott WolfApril 6, 2017
- 150Jason Statham, Rashida Jones, Tim Morehouse, guest co-host Scott WolfApril 7, 2017
- 151Vin Diesel, guest co-host Morris ChestnutApril 10, 2017
- 152David Duchovny, Joey McIntyre, guest co-host Morris ChestnutApril 11, 2017
- 153Hank Azaria, guest co-host Morris ChestnutApril 12, 2017
- 154Anna Chlumsky, guest co-host Carrie Ann InabaApril 13, 2017
- 155Guest co-host Carrie Ann InabaApril 14, 2017
- 156Jennifer Hudson, Josh Lucas, guest co-host Priyanka ChopraApril 17, 2017
- 157Kristin Chenoweth, Renee Elise Goldsberry, guest co-host Jussie SmollettApril 18, 2017
- 158Rose Byrne, Bella Thorne, guest co-host Jussie SmollettApril 19, 2017
- 159Bob Odenkirk, Katherine Heigl, guest co-host Van JonesApril 20, 2017
- 160Rosario Dawson, Rick Schwartz, Zara Larsson, Clean Bandit, guest co-host Van JonesApril 21, 2017
- 161Cobie Smulders, Nikolaj Coster-Waldau, guest co-host John LeguizamoApril 24, 2017
- 162Caitlyn Jenner, Andrew Zimmern, guest co-host John LeguizamoApril 25, 2017
- 163John Legend, Molly Ringwald, guest co-host John LeguizamoApril 26, 2017
- 164America Ferrera, guest co-host John LeguizamoApril 27, 2017
- 165LL Cool J, Lea Michele, guest co-host John LeguizamoApril 28, 2017